31 Dic. 2016

Nestin+cells forming spheroids aggregates resembling tumorspheres in experimental ENU-induced gliomas

Nestin+cells from spheroid aggregates display typical histopathological features compatible with cell stemness. Nestin and CD133+cells found in glioblastomas, distributed frequently around aberrant vessels, are considered as potential cancer stem cells. They are possible targets for antitumoral therapy because they lead the tumorigenesis, invasiveness and angiogenesis. However, little is known about ...

ENLACE
15 Oct. 2016

Clinical considerations and surgical approaches for low-grade gliomas in deep hemispheric locations: insular lesions

Insula and paralimbic region represent a common location for gliomas in adulthood. However, limbic and paralimbic tumors are rare in children. Reports of pediatric insular tumors are scarce in literature, and most of them are included in adult's series, so their management and outcome can be outlined only after extracting ...

ENLACE
10 Mar. 2016

Long-term impact on quality of life of subthalamic nucleus stimulation in Parkinson's disease

Long-term impact of bilateral subthalamic nucleus deep brain stimulation (STN-DBS) on health-related quality of life (HRQOL) and associated factors in patients with Parkinson's disease (PD) are not clear. In this prospective study, we included 69 PD patients (64 % men, mean age 61.3 ± 7.4 and disease duration 13.2 ± ...

ENLACE